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Last pushed: 2 years ago
Short Description
An image that allows users to run the Decombinator TCR analysis pipeline.
Full Description

The ligation-mediated 5'RACE protocol for T-cell receptor repertoire amplification developed under Benny Chain in the Innate2Adaptive laboratory at UCL allows for unbiased amplification and extraction of error-corrected TCR sequences. The FASTQ data produced requires suitable demultiplexing prior to VJ assignation using Decombinator, and subsequent error-correction/frequency collapsing and CDR3 extraction. Scripts for all of these functions have been developed in Python (v2.7).

This repository hosts a Docker image that allows users to run these scripts without having to install Python or any of the dependencies required by the pipeline.

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decombinator