Public Repository

Last pushed: 24 days ago
Short Description
RNA motif finder for the recovery of sequence-structure motifs from RNA-binding protein data.
Full Description

RNA-binding proteins (RBPs) play a vital role in the post-transcriptional control of RNAs. They are known to recognize RNA molecules by their nucleotide sequence as well as their three-dimensional structure. ssHMM is an RNA motif finder that combines a hidden Markov model (HMM) with Gibbs sampling to learn the joint sequence and structure binding preferences of RBPs from high-throughput RNA-binding experiments, such as CLIP-Seq. The model can be visualized as an intuitive graph illustrating the interplay between RNA sequence and structure.

Github: https://github.molgen.mpg.de/heller/ssHMM
Documentation: http://sshmm.readthedocs.io
License: GNU General Public License

Docker Pull Command
Owner
hellerd