davidebrex/spikeflow repository overview

Docker container to run SpikeFlow (https://github.com/DavideBrex/SpikeFlow⁠) with Snakemake.

SpikeFlow is a Snakemake-based workflow designed for the analysis of ChIP-seq data with spike-in normalization (i.e. ChIP-Rx). Spike-in controls are used to provide a reference for normalizing sample-to-sample variation. These controls are typically DNA from a different species added to each ChIP and input sample in consistent amounts. This workflow facilitates accurate and reproducible chromatin immunoprecipitation studies by integrating state-of-the-art computational methodologies.