genehetx/vep_hs repository overview

This docker image allows to perform variant annotation using VEP (Homo sapiens GRCh38 )

Command line : (example)

vep -i file.vcf -o out.vcf --offline --cache --dir_cache /opt/vep/.vep --sift p,s,b --variant_class --nearest gene --gene_phenotype --hgvs --protein --symbol --canonical --mane --var_synonyms --vcf

You can use different parameters (https://www.ensembl.org/info/docs/tools/vep/script/vep_options.html⁠)