hwangstephen/memo repository overview

Maximal Exact Match Ordered (MEMO) is a pangenome indexing method based on maximal exact matches (MEMs) between genomes. A single MEMO index can handle arbitrary-length k-mer queries over pangenomic windows. MEMO performs membership queries for per-genome k-mer presence/absence and conservation queries for the number of genomes containing the k-mers in a window. MEMO achieves smaller index sizes and faster queries than k-mer-based approaches like KMC3 and PanKmer. See the Github repo for MEMO here⁠.