nlesc/nplinker repository overview

⁠Natural Products Linker (NPLinker)

NPLinker aims to address the significant bottleneck that exists in the realisation of the potential of genome-led metabolite discovery, namely the slow manual matching of predicted biosynthetic gene clusters (BGCs) with metabolites produced during bacterial culture; linking phenotype to genotype.

NPLinker implements a new data-centric approach to alleviate this linking problem by searching for patterns of strain presence and absence between groups of similar spectra (molecular families; MF) and groups of similar BGCs (gene cluster families; GCF). Searches can be performed using a number of available analysis methods employed in isolation or together.

⁠Usage

This docker image contains both backend and frontend of NPLinker. Please check our Github wiki page⁠ for more info about running and interacting with NPLinker (webapp).

⁠Contributing

If you want to contribute to the development of nplinker, have a look at the contribution guidelines⁠ and README for developers⁠.