openeuler/hh-suite repository overview

⁠Quick reference

• The official HH-suite docker image.
• Maintained by: openEuler CloudNative SIG⁠.
• Where to get help: openEuler CloudNative SIG⁠, openEuler⁠.

⁠HH-suite | openEuler

HH-suite3 is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs), developed by the Soding lab. HH-suite provides:

• HHblits: Fast iterative HMM search for remote homology detection and deep protein annotation.
• HHsearch: Sensitive HMM-HMM alignment for profile-profile comparison.
• HHPred: Protein structure and function prediction via profile-profile search.
• SIMD acceleration: SSE2/AVX2 on x86_64, NEON on ARM64 for high-performance sequence alignment.
• MPI parallel computation support (self-compiled version only).
• Multi-format input support: FASTA, A3M, HMM, and HHM profiles.
• Extensive database integration: Uniclust30, BFD, Pfam, SCOP, PDB70, and more. Learn more at HH-suite⁠.

⁠Supported tags and respective Dockerfile links

The tag of each HH-suite docker image is consist of the version of HH-suite and the version of basic image. The details are as follows:

⁠Usage

• Ensure that you have Docker installed, or are using Docker for Linux containers if on Windows.
• Obtain the HH-suite docker image from DockerHub: docker pull openeuler/hh-suite:{Tag}
• Run the Docker container to launch the HH-suite environment. docker run -it openeuler/hh-suite:{Tag}
• Verify the installation inside the container: hhblits -h && hhsearch -h

⁠Question and answering

If you have any questions or want to use some special features, please submit an issue or a pull request on openeuler-docker-images⁠.