pavlopouloslab/flame repository overview

⁠Welcome to Flame (v2.0)

Visualization and interpretation of functional and literature enrichment analysis results from multiple sets With Flame one can:

• Upload multiple gene/protein lists, SNPs, free text or gene expression results (Volcano plot)
• Combine lists by calculating their unions and intersections with the help of UpSet plots
• Perform functional enrichment analysis on any of the combined lists for more than 14,000 organisms, using four tools (aGOtool, gProfiler, WebGestalt, enrichR)
• Combine and compare enrichment results from multiple runs
• Perform literature enrichment analysis on any of the combined lists, using aGOtool
• Generate protein-protein interaction networks via STRING
• Visualize results with the use of networks, heatmaps, bar charts, scatter plots and searchable tables
• Perform network analysis at the gene-function, function-function and gene-gene association levels
• Visualize networks in interactive, multi-layered views with Arena3Dweb
• Combine data sources and apply interactive filters on the generated plots
• Perform cross-database and cross-species id conversions
• Utilize our API to connect Flame with external applications

Web Application: http://flame.pavlopouloslab.info

Code: https://github.com/PavlopoulosLab/FLAME⁠

Docker: https://hub.docker.com/r/pavlopouloslab/flame⁠

⁠Please cite:

1. Flame: A web tool for functional and literature enrichment analysis using multiple gene lists
   Thanati F., Karatzas E., Baltoumas F., Stravopodis DJ., Eliopoulos AG., Pavlopoulos GA
   Biology,14 Jul 2021, 10(7), 665; https://doi.org/10.3390/biology10070665⁠
   PMID:34356520⁠

⁠How to run:

1. Pull the image to your machine:

1. Create a container for the image using a port of your choice, e.g. 3838: