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tumordeconv/mrna-data

By tumordeconv

•Updated over 2 years ago

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tumordeconv/mrna-data repository overview

⁠mRNA Module

This module enables the collection of mRNA patient data using the cptac Python package to collect mRNA data for one of six available cancer types. This module includes the following:

File nameDescription
getAllDatasets.pyThis script is run within the Docker build process to get all datasets into the Python environment
mRNADataSetsCLI.pyThis script is the primary tool to pull a specific cancer data type
DockerfileThis file contains the two scripts above and the cptac Python package
mrna-data-cwl-tool.cwlThis is a CWL tool to run the Docker image with the command line tool

⁠To run

There are three ways to get mRNA data, depending on your environment. Each one should output a file.tsv in your local directory

⁠If you have Python and cptac installed

Simply run the command

python mRNADataSetsCLI.py --cancerType=brca

⁠If you have Docker installed

Then you can run the command via the docker interactive mode

docker build . -t mrna-module
docker run --volume $PWD:/tmp -ti mrna-module mRNADataSetsCLI.py --cancerType=brca
⁠If you have Docker and a CWL engine

Here we have an example using the cwl-tool engine, but this should run any other engine as well.

cwl-tool mrna-data-cwl-tool.cwl --cancerType brca

⁠Cancer types

Dataset nameDescriptionData reuse statusPublication link
Brcabreast cancerno restrictionshttps://pubmed.ncbi.nlm.nih.gov/33212010/⁠
Ccrccclear cell renal cell carcinoma (kidney)no restrictionshttps://pubmed.ncbi.nlm.nih.gov/31675502/⁠
Coloncolorectal cancerno restrictionshttps://pubmed.ncbi.nlm.nih.gov/31031003/⁠
Endometrialendometrial carcinoma (uterine)no restrictionshttps://pubmed.ncbi.nlm.nih.gov/32059776/⁠
**Gbmglioblastomapassword access onlyunpublished**
Hnscchead and neck squamous cell carcinomano restrictionshttps://pubmed.ncbi.nlm.nih.gov/33417831/⁠
**Lscclung squamous cell carcinomapassword access onlyunpublished**
Luadlung adenocarcinomano restrictionshttps://pubmed.ncbi.nlm.nih.gov/32649874/⁠
Ovarianhigh grade serous ovarian cancerno restrictionshttps://pubmed.ncbi.nlm.nih.gov/27372738/⁠
**Pdacpancreatic ductal adenocarcinomapassword access onlyunpublished**

As such, datasets have been updated to following (added hnscc): ['brca', 'ccrcc', 'endometrial', 'colon', 'ovarian', 'hnscc', 'luad']

Tag summary

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Image

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sha256:788fa6f02…

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519.5 MB

Last updated

over 2 years ago

docker pull tumordeconv/mrna-data